The purpose of this study was to observe the origin and nature of the salivary gland mixed tumor. Using 4 specimens, after final diagnosis as pleomorphic adenoma was decided under light microscope, ultrastructural and histological examination on it was done under H-600 electron microscope.
The results were as followed:
1. The tumor cell was composed of epithelial and myoepithelial cells.
2. In the epithelial cells, polygonal or avoid tubular structures were observed and squamous epithelial cells and keratin pearls were present, and they were embedded on fibrous Or myxoid stroma. In the tubular structures, eosinophiiic coagu um was observed.
3. The abundant cytoplasm had microvillous projections and well developed rough endoplasmic reticulums were dilated, and numerous vacuoles were observed in the cytoplasm.
4. The nuclei of epithelial cells were round, irregular, dispersed and also had occasionally nucleoli.
5. The myoepithelial cells had endoplasmic fibrilloid structures, and intermixed with epithelial cells.
6. The eosinophilic material and hyalinized connective tissues were characteristic, and stroma was uniform, dense, and composed of fibrilloid and myxoid elements, chiefly fibrilloid.
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